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Leg heaviness and stasis microangiopathy. Preventive and therapeutic approaches
Henry F , Paquet P , Pierard-Franchimont C , Pierard GE
Rev Med Liege 2003, 58(6),435-438Abstract : Venous insufficiency of the legs is a frequent and insidious disorder which, through its consequences' cascade, lead to some cutaneous microangiopathy with relative ischemia. Chronic leg ulcer is the late issue of the process accompanied by varied medical and socio-economic aspects. The pathogeny of the cutaneous lesions is directly related to alterations in hemorrheology and leukocyte adhesion inside capillaries. Elastic contention and some venotropic drugs exert preventive effects on the development of leg ulcers. They also bring some therapeutic improvement of the symptoms of leg heaviness