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The large cell anaplastic lymphoma associated with breast implants
Van Boeckel V , Duysinx O , Vrancken K , Nizet C , Nelissen X , Nizet J-L
Rev Med Liege 2025, 80(7-8),529-533Abstract : Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare CD-30+/ALK- T-cell lymphoma. The combination of a textured breast implant, bacterial contamination and genetic predisposition appears to be necessary for the development of BIA-ALCL. The National Comprehensive Cancer Network (NCCN) has established guidelines for both diagnosis and treatment. Early detection of the disease is essential to ensure a cure. At an early stage and for the vast majority of patients, treatment consists of implant removal with associated total capsulectomy. We share our experience with the presentation of a case of BIA-ALCL discovered following the appearance of a periprosthetic seroma, 19 years after the fitting of breast implants.
