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Involvement of matrix metalloproteinases in obstetrics : from implantation to delivery
Christiane Y. , Emonard V. , Emonard H.
Rev Med Liege 2014, 69(1),46-50Abstract : Matrix metalloproteinases, which remodel the extracellular matrix, are involved in all physiological and pathophysiological processes. In particular, they contribute to the success of a pregnancy : from embryo implantation in the endometrium to uterine cervical ripening and uterine involution. A misregulation of their expression and/or of their activity is observed in two major diseases in pregnancy such as spontaneous abortion and preeclampsia.
