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Virus-induced cancers : interplay between genetics and environment
Delvenne P. , Renoux V.M. , Ara fa M. , Trimeche M. , Christophe J. , Kridelka F. , Piérard G.E.
Rev Med Liege 2012, 67(5-6),381-389Abstract : Among cancers diagnosed worldwide on a yearly basis, 20% are thought to be associated with a viral infection. The viruses involved are, by order of decreasing incidence, the hepatitis viruses, the papillomaviruses and the Epstein-Barr virus. These virus-induced cancers generate a high level of interest not only for the study of mechanisms involved in the neoplastic transformation, but also for the set-up of specific immunotherapies including prophylactic and therapeutic antitumor vaccination.
