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Dementia in Parkinson’s disease :risk factors, diaiagnosis and treatment
Bakay S. , Bechet S. , Barjona A. , Delvaux V. , Salmon E. , Garraux G.
Rev Med Liege 2011, 66(2),75-81Abstract : Aside from limb tremor, bradykinesia, rigidity and gait disturbances, Parkinson’s disease (PD ) is also characterized by non-motor symptoms. A cognitive decline can occur early in the disease course and undoubtedly impact of the patient’s quality of life. Dementia affects 80% of patients 20 years after disease onset but a small subgroup of patients remain free of dementia even after decades with PD . Risk factors and diagnosis of dementia can be easily assessed using bed-side clinical instruments. Advances in genetics and imagery will allow improving the diagnosis and therapeutic strategy of dementia in Parkinson’s disease.
