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The calcipotriol-betamethasone dipropionate association
Henry F , Flagothier C , Delvoye P , Piérard-Franchimont C , Piérard GE
Rev Med Liege 2005, 60(11),893-895Abstract : The topical treatment of psoriasis benefits from the alternate use of dermocorticosteroids and vitamin D3 analogues. A new galenic formulation allows to combine them in a single application. Dovobet® (LEO Pharma) ointment is the association of calcipotriol 50 µg/g with betamethasone dipoprionate 0.5 mg/g. This formulation boosts the therapeutic activity of calcipotriol. It also decreases the irritative inflammatory reaction due to calcipotriol without increasing the atrophogenic risk of the dermocorticoid.
